Ruthenium‐Catalyzed Oxidant‐Free Allylation of Aromatic Ketoximes with Allylic Acetates at Room Temperature

Abstract

Substituted aromatic ketoximes reacted efficiently with allylic acetates in the presence of {[RuCl2(p‐cymene)]2} and AgSbF6 in 1,2‐dichloroethane at ambient temperature, providing ortho‐allyl aromatic ketoximes in a highly regioselective manner without an oxidant. In the reaction, the acetate group of allyl acetate acts as a base to activate the CH bond of aromatics. Later, ortho‐allyl aromatic ketoximes were converted into ortho‐allyl aromatic ketones in the presence of HCl.