IISER Pune Digital Repository

A repository of scholarly research output from the Indian Institute of Science Education and Research (IISER) Pune.

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Recent Submissions

  • Item type:Item,
    Overview of the ASM-IISc Symposium on the One Health Approach to AMR in Bengaluru, India
    (American Society for Microbiology, 2026-08) Anand, Amitesh; MATANGE, NISHAD; Pande, Samay; Bhandari, Vasundhra; Dept. of Biology
    Antimicrobial resistance (AMR) is a systemic global threat, frequently described as a silent pandemic due to the challenges in attributing mortality to drug-resistant infections. Addressing this crisis necessitates a paradigm shift from viewing AMR as a linear consequence of antibiotic exposure to understanding it as an emergent property of ecological systems and metabolic plasticity. The ASM-IISc Symposium on the One Health Approach to AMR brought together a multidisciplinary cohort to deliberate on the drivers and solutions for resistance at the intersection of human, animal, and environmental health. Key thematic deliberations highlighted the role of technology in predicting resistance evolution and identifying novel targets for drug combinations. Furthermore, the symposium underscored the necessity of ecology-driven surveillance, extending genomic monitoring to environmental reservoirs. Ultimately, these findings establish a roadmap toward proactive, predictive, and integrated One Health strategies. Solutions demand mechanistic research and ecosystem-level interventions that bridge molecular insight with global public health strategy.
  • Item type:Item,
    Search for Higgs boson production at high transverse momentum in the WW decay channel in proton-proton collisions at √(s) = 13 TeV.
    (Springer Nature, 2026-07) CMS Collaboration; Hayrapetyan, A.; DUBE, SOURABH; HAZARIKA, P.; KANSAL, B.; LAHA, A.; SHARMA, R.; SHARMA, SEEMA; VAISH, K.Y. et al.; Dept. of Physics
    A search for Higgs boson (H) production at high transverse momentum (pT) in the WW decay channel is presented. The analysis uses proton-proton collisions at TeV recorded by the CMS experiment in 2016–2018, corresponding to an integrated luminosity of 138 fb−1. The visible decay products of the Higgs boson are reconstructed as a single large-radius jet with one isolated lepton or none (1ℓ and 0ℓ, respectively; ℓ = e, μ). The H-candidate jets are identified using an advanced transformer-based algorithm and are calibrated with the Lund jet plane reweighting technique. The 1ℓ channel is further split into gluon fusion, vector boson fusion, and associated production with hadronically decaying vector boson categories, while the 0ℓ channel considers all production processes inclusively. The measured cross section times the H → WW branching fraction relative to the standard model expectation is , indicating no evidence of a signal above the background. This measurement represents the first dedicated study of highly Lorentz-boosted H → WW decays, complementing earlier searches for high-pT Higgs boson in other decay channels.
  • Item type:Item,
    Search for exotic Higgs boson decays H → AA with A → YY in events with a semi-merged topology in proton-proton collisions at √(s) = 13 TeV.
    (Springer Nature, 2026-07) CMS Collaboration; Hayrapetyan, A.; ALPANA, A.; DUBE, SOURABH; HAZARIKA, P.; KANSAL, B.; LAHA, A.; SHARMA, R.; SHARMA, SEEMA; VAISH, K.Y. et al.; Dept. of Physics
    A search for exotic Higgs boson decays H → 𝒜𝒜, with 𝒜 → γγ is presented, using events with a semi-merged topology. One of the hypothetical particles, 𝒜, is assumed to decay promptly into a semi-merged diphoton system reconstructed as a single photon-like object, while the other 𝒜 decays into two resolved photons. The search is performed using proton-proton collision data collected by the CMS experiment at TeV, corresponding to an integrated luminosity of 138 fb−1. The data agree with the standard model background expectation. Upper limits are set on the product of the Higgs boson production cross section and the branching fraction, σ(pp → H) ℬ(H → 𝒜𝒜 → 4γ), which range from 0.264 to 0.005 pb at 95% confidence level, for 𝒜 masses in the range 1 < m𝒜 < 15 GeV. These limits are the most stringent to date in the 1–5 GeV m𝒜 range.
  • Item type:Item,
    Grassland destruction causes shifts in plant traits that persist during recovery
    (National Academy of Sciences, 2026-08) NERLEKAR, ASHISH N.; Giles, André et al.; Dept. of Biology
    Old-growth grasslands assemble over millennia and support high biodiversity and many ecosystem services, but continue to undergo widespread destruction for production of crops, timber, and minerals. How biodiversity recovers after grassland destruction and the functional consequences of this recovery can be informed by plant functional traits—i.e., morpho-physiological features that influence growth, survival, and reproduction. Yet we lack understanding of how functional traits differ between old-growth and secondary (i.e., recovering) grassland plant species at the global scale, hindering understanding of community assembly processes that transcend geographical regions. Addressing this gap, we synthesized trait data for 742 plant species from 24 studies across six continents to understand how plant species indicative of old-growth and secondary grasslands compare in their traits. Compared to old-growth grasslands, plants indicative of secondary grasslands were taller and had leaves with more nitrogen content, higher specific leaf area, and lower dry-matter content. Notably, these trait differences that make old-growth grassland plants more resource conservative and secondary grassland plants more resource acquisitive persisted over a century. Taken together, these findings help to explain why many secondary grasslands support altered plant communities for decades to centuries and emphasize the importance of old-growth grassland conservation in the light of the unique plant forms and functions they support. Persistent trait shifts associated with grassland destruction could accelerate nutrient cycling, and our findings provide guidance for recovering old-growth grassland biodiversity through ecological restoration.
  • Item type:Item,
    Active Tectonics of the Eastern and Southern Alps ‐ Crustal Response to Deep Processes? A Review
    (WIley, 2026-08) Grützner, Christoph; KUMAR, AJAY; Dept. of Earth and Climate Science
    Owing to the low N‐S convergence rates between Adria and Europe, crustal deformation rates in the Alps and its forelands are low. Active tectonics are, therefore, difficult to study, especially as non‐tectonic landscape forming processes can erase or modify the tectonic surface imprint. Large‐scale and dense seismological data recently offered insights into earthquakes and into the lithospheric structure beneath the Alps. Recent field studies added data on geological archives of active tectonics. In this review, we summarize the results from studies of seismic tomography, geodesy, seismology, historical seismology, archeoseismology, on‐fault and off‐fault paleoseismology, and fault gouge dating, focusing on the eastern part of the Alps during the last c. 1 Ma. We discuss the influence of the lithosphere on the localization of deformation, and we draw a generalized picture of active deformation. We show that deformation is primarily accommodated across the South Alpine Front (∼2 mm/yr out of max 3 mm/yr total shortening) and NW‐SE striking strike‐slip faults in western Slovenia (∼1.5 mm/yr shear). Large fault systems in the interior of the Eastern Alps are still actively accommodating extrusion of crustal material toward the east at very low rates (0.5–1.0 mm/yr). Diffuse deformation and clusters of seismicity are observed in the interior of the Alps. Minor shortening occurs at the North Alpine Front. Crustal strength controls the localization of deformation resulting in non‐deforming blocks. Neogene slab break‐off events do not control the present‐day deformation. Instead, present‐day uplift of 1.5–2 mm/yr correlates to areas glaciated during the Last Glacial Maximum.