Synthesis of Tetrasubstituted Symmetrical Pyrazines from β‐Keto γ‐Amino Esters: A Mild Strategy for Self‐Dimerization of Peptides
| dc.contributor.author | Kumar, Mothukuri Ganesh | en_US |
| dc.contributor.author | Thombare, Varsha J. | en_US |
| dc.contributor.author | BHAISARE, RUPAL DINESH | en_US |
| dc.contributor.author | Adak, Anindita | en_US |
| dc.contributor.author | GOPI, HOSAHUDYA N. | en_US |
| dc.contributor.department | Dept. of Chemistry | en_US |
| dc.date.accessioned | 2019-03-15T11:22:37Z | |
| dc.date.available | 2019-03-15T11:22:37Z | |
| dc.date.issued | 2015-01 | en_US |
| dc.description.abstract | A facile synthesis of highly symmetrical tetrasubstituted pyrazines through simple aerial oxidation of β‐keto γ‐amino esters is reported. The scope of the reaction was examined by use of various amino acid side‐chain functional groups and peptides. The mild and efficient transformation of β‐keto γ‐amino esters into pyrazines may serve as an attractive strategy for self‐dimerization of peptides. | en_US |
| dc.identifier.citation | European Journal of Organic Chemistry, 2015(1), 135-141. | en_US |
| dc.identifier.issn | 1434-193X | en_US |
| dc.identifier.issn | 1099-0690 | en_US |
| dc.identifier.sourcetitle | European Journal of Organic Chemistry | en_US |
| dc.identifier.uri | http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2144 | |
| dc.identifier.uri | https://doi.org/10.1002/ejoc.201403237 | |
| dc.language.iso | en | en_US |
| dc.publication.originofpublisher | Foreign | en_US |
| dc.publisher | Wiley | en_US |
| dc.subject | Synthesis of Tetrasubstituted Symmetrical | en_US |
| dc.subject | γ‐Amino Esters | en_US |
| dc.subject | Mild Strategy | en_US |
| dc.subject | Self‐Dimerization of Peptides | en_US |
| dc.subject | Heterocyclic aromatic compounds | en_US |
| dc.subject | 2015 | en_US |
| dc.title | Synthesis of Tetrasubstituted Symmetrical Pyrazines from β‐Keto γ‐Amino Esters: A Mild Strategy for Self‐Dimerization of Peptides | en_US |
| dc.type | Article | en_US |