Novel Bifunctional Photoactivable Fluorescent Lipid Probes for Proximity Labelling-Based Identification of Membrane-Associated Proteins

Abstract

This invention discloses bi-functional photoactivable fluorescent lipid probes for proximity labelling-based identification of membrane-associated proteins, and synthesis thereof. The photoactivable fluorescent lipid probe include a lipid moiety, a fluorophore, and a photoactivable moiety; where the fluorophore and the photoactivable moiety are covalently attached to the lipid moiety.