Assessing the effect of different shapes of glyco-gold nanoparticles on bacterial adhesion and infections

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dc.contributor.authorChaudhary, Preeti Madhukaren_US
dc.contributor.authorSangabathuni, Sivakotien_US
dc.contributor.authorMurthy, Raghavendra Vasudevaen_US
dc.contributor.authorPaul, Ajayen_US
dc.contributor.authorThulasiram, Hirekodathakallu V.en_US
dc.contributor.authorKIKKERI, RAGHAVENDRAen_US
dc.contributor.departmentDept. of Chemistryen_US
dc.date.accessioned2019-03-15T11:23:08Z
dc.date.available2019-03-15T11:23:08Z
dc.date.issued2015-08en_US
dc.description.abstractAchieving selective and sensitive carbohydrate-protein interactions (CPIs) using nanotechnology is an intriguing area of research. Here we demonstrate that the different shapes of gold nanoparticles (AuNPs) functionalized with monosaccharides tune the bacterial aggregations. The mechanism of aggregation revealed that the large number of surface interactions of rod shaped mannose-AuNPs with E. coli ORN 178 compared with spherical and star-shaped AuNPs exhibited higher avidity and sensitivity. Moreover, such sensitive binding can be used for effective inhibition of bacterial infection of cells.en_US
dc.identifier.citationChemical Communications, 51(86),15669-15672.en_US
dc.identifier.issn1359-7345en_US
dc.identifier.issn1364-548Xen_US
dc.identifier.sourcetitleChemical Communicationsen_US
dc.identifier.urihttp://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2163
dc.identifier.urihttps://doi.org/10.1039/C5CC05238F
dc.language.isoenen_US
dc.publication.originofpublisherForeignen_US
dc.publisherRoyal Society of Chemistryen_US
dc.subjectGlyco-gold nanoparticlesen_US
dc.subjectBacterial adhesionen_US
dc.subjectInfectionsen_US
dc.subjectMonosaccharidesen_US
dc.subject2015en_US
dc.titleAssessing the effect of different shapes of glyco-gold nanoparticles on bacterial adhesion and infectionsen_US
dc.typeArticleen_US

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