A highly selective sulfinate ester probe for thiol bioimaging
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Royal Society of Chemistry
Abstract
We describe here hitherto unexplored chemistry of the sulfinate ester functional group as being highly selective towards nucleophilic substitution by thiols at physiological pH. Using this cleavable trigger, an optical thiol probe that is suitable for thiol bioimaging has been developed.
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Citation
Chemical Communications, 50(78), 11533-11535.