A convenient protocol for the deprotection of N-benzyloxycarbonyl (Cbz) and benzyl ester groups

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dc.contributor.authorSULTANE, PRAKASH R.en_US
dc.contributor.authorMete, Trimbak B.en_US
dc.contributor.authorBHAT, RAMAKRISHNA G.en_US
dc.contributor.departmentDept. of Chemistryen_US
dc.date.accessioned2019-03-15T11:22:37Z
dc.date.available2019-03-15T11:22:37Z
dc.date.issued2015-04en_US
dc.description.abstractWe describe a convenient and practical method for the deprotection of N-benzyloxycarbonyl (Cbz) and benzyl ester groups using NaBH4 and catalytic Pd–C in methanol. Deprotection was very facile and rapid. In situ generation of hydrogen is certainly user friendly and avoids the use of a hydrogen cylinder. In order to establish the wider applicability of this approach, deprotection has also been demonstrated in gram scale reactionsen_US
dc.identifier.citationTetrahedron Letters, 56(16), 2067-2070.en_US
dc.identifier.issn0040-4039en_US
dc.identifier.sourcetitleTetrahedron Lettersen_US
dc.identifier.urihttp://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/2139
dc.identifier.urihttps://doi.org/10.1016/j.tetlet.2015.02.131
dc.language.isoenen_US
dc.publication.originofpublisherForeignen_US
dc.publisherElsevier B.V.en_US
dc.subjectNatural productsen_US
dc.subjectAmino acidsen_US
dc.subjectDeprotectionen_US
dc.subjectHydrogenolysisen_US
dc.subjectPracticabilityen_US
dc.subject2015en_US
dc.titleA convenient protocol for the deprotection of N-benzyloxycarbonyl (Cbz) and benzyl ester groupsen_US
dc.typeArticleen_US

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