The Construction of Carbon-Heteroatom Bonds (C-X; X = N, O, S) Under Metal-Free Conditions to Access Useful Heterocyclic Scaffolds

Abstract

The construction of heterocyclic scaffolds through a carbon-heteroatom bond (C–N, C–O, C–S) forming reactions have gained significant attention in organic synthesis over the years. The construction of carbon-heteroatom bonds is of great interest to building biologically active compounds, natural products, various polymers and materials. Various novel strategies have been developed to construct the carbon-heteroatom bonds to access heterocyclic scaffolds and some of the selected carbon-heteroatom bond forming reactions have been highlighted in this thesis.