DNA Nanocarriers: Programmed to Deliver

Abstract

DNA can be used as a building block for creating nanoscale structures.DNA nanostructures are programmable, offering unique characteristics for use as drug delivery carriers.DNA nanocarriers can be targeted to specific cells; be triggered using chemical, molecular or environment cues to release drugs; and offer tunable cellular uptake profiles.DNA nanocarriers are used for a variety of cargos including small molecules, therapeutic oligonucleotides, antibodies, peptides, and photosensitizers.Nanocarriers can be functionalized to provide a -see-and-treat- strategy for the creation of theranostics.