Gap junctions and excitation patterns in continuum models of islets

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dc.contributor.authorGOEL, PRANAYen_US
dc.contributor.authorSneyd, Jamesen_US
dc.contributor.departmentDept. of Mathematicsen_US
dc.date.accessioned2019-07-23T11:33:27Z
dc.date.available2019-07-23T11:33:27Z
dc.date.issued2012-09en_US
dc.description.abstractWe extend the development of homogenized models for excitable tissues coupled through "doughball" gap junctions. The analysis admits nonlinear Fickian fluxes in rather general ways and includes, in particular, calcium-gated conductance. The theory is motivated by an attempt to understand wave propagation and failure observed in the pancreatic islets of Langerhans. We reexamine, numerically, the role that gap junctional strength is generally thought to play in pattern formation in continuum models of islets.en_US
dc.identifier.citationDiscrete and Continuous Dynamical Systems - Series B, 17(6), 1969-1990.en_US
dc.identifier.issn1531-3492en_US
dc.identifier.issn1553-524Xen_US
dc.identifier.sourcetitleDiscrete and Continuous Dynamical Systems - Series Ben_US
dc.identifier.urihttp://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3734
dc.identifier.urihttps://doi.org/10.3934/dcdsb.2012.17.1969
dc.language.isoenen_US
dc.publication.originofpublisherForeignen_US
dc.publisherAmerican Institute of Mathematical Sciencesen_US
dc.subjectGap junctionsen_US
dc.subjectExcitation patternsen_US
dc.subjectContinuum models of isletsen_US
dc.subject2012en_US
dc.titleGap junctions and excitation patterns in continuum models of isletsen_US
dc.typeArticleen_US

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