A One Pot Transition‐Metal‐Free Synthesis of Styrenyl Ethers from 2‐Aryloxy/Alkoxy Acetophenones

Abstract

A one-pot transition-metal-free synthesis of styrenyl ethers starting from 2-aryloxy/alkoxy acetophenones is described. The protocol explores the use of tosyl hydrazide and potassium carbonate as a mild base via Bamford-Stevens reaction to synthesize the styrenyl ethers. The protocol is very simple, practical and uses mild reaction conditions with simple reaction set-up. This practical protocol proved to be scalable on gram quantity.