Role of MADF BESS Domain Protein Family In Gene Regulation and Wing Development in Drosophila melanogaster

dc.contributor.advisor	RATNAPARKHI, GIRISH S.	en_US
dc.contributor.author	KULKARNI, APURV	en_US
dc.contributor.department	Dept. of Biology	en_US
dc.contributor.registration	20081010	en_US
dc.date.accessioned	2013-05-14T10:32:07Z
dc.date.available	2013-05-14T10:32:07Z
dc.date.issued	2013-05	en_US
dc.description.abstract	In Drosophila melanogaster, there are 16 genes listed in the MADF-BESS domain family. Three out of these sixteen genes -- hinge1 (CG9437), hinge2 (CG13897) and hinge3 (CG8359) -- have been shown to give a bent wing phenotype when knocked down by RNA interference. I have characterized the phenotype that results from knock down of hinge1 using flight assays, light microscopy and scanning electron microscopy. I found out that hinge1, hinge2 and hinge3 are negative regulators of wingless, the best characterized wnt gene in Drosophila melanogaster.	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/269
dc.language.iso	en	en_US
dc.subject	2013	en_US
dc.subject	Developmental Biology	en_US
dc.title	Role of MADF BESS Domain Protein Family In Gene Regulation and Wing Development in Drosophila melanogaster	en_US
dc.type	Thesis	en_US
dc.type.degree	BS-MS	en_US

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