A Vinyl-Boronate Ester-Based Persulfide Donor Controllable by Hydrogen Peroxide, a Reactive Oxygen Species (ROS)

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dc.contributor.authorBORA, PRERONAen_US
dc.contributor.authorChauhan, Preetien_US
dc.contributor.authorMANNA, SUMANen_US
dc.contributor.authorCHAKRAPANI, HARINATHen_US
dc.contributor.departmentDept. of Chemistryen_US
dc.date.accessioned2019-01-24T09:14:14Z
dc.date.available2019-01-24T09:14:14Z
dc.date.issued2018-12en_US
dc.description.abstractA vinyl boronate ester-based persulfidating agent that is selectively activated by hydrogen peroxide, which is a reactive oxygen species (ROS), and efficiently generated a persulfide by a hitherto unexplored 1,4-O,S-relay mechanism is reported. This donor was found to protect cells from cytotoxicity induced by oxidants, and the major byproduct is cinnamaldehyde, which is widely used in the food industry as an additive.en_US
dc.identifier.citationOrganic Letters, Vol. 20(24) pp7916-7920.en_US
dc.identifier.issn1523-7060en_US
dc.identifier.issn1523-7052en_US
dc.identifier.sourcetitleOrganic Lettersen_US
dc.identifier.urihttp://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1554
dc.identifier.urihttps://doi.org/10.1021/acs.orglett.8b03471
dc.language.isoenen_US
dc.publication.originofpublisherForeignen_US
dc.publisherAmerican Chemical Societyen_US
dc.subjectSmall-Moleculeen_US
dc.subjectMycobacterium-Tuberculosisen_US
dc.subjectEquilibrium-Constantsen_US
dc.subjectSulfide Protectsen_US
dc.subjectChemical Biologyen_US
dc.subjectKeto-Enolen_US
dc.subjectDisulfidesen_US
dc.subjectGenerationen_US
dc.subjectActivationen_US
dc.subjectPrecursorsen_US
dc.subjectTOC-JAN-2019en_US
dc.subject2018en_US
dc.titleA Vinyl-Boronate Ester-Based Persulfide Donor Controllable by Hydrogen Peroxide, a Reactive Oxygen Species (ROS)en_US
dc.typeArticleen_US

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