A facile transformation of amino acids to functionalized coumarins
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Royal Society of Chemistry
Abstract
The synthesis of novel chiral coumarins functionalized with proteinogenic amino acid side chains via N-protected γ-amino-β-keto esters and their incorporation into the cell permeable HIV-1 TAT peptide through the modified solid phase peptide synthesis are described.
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Citation
Organic & Biomolecular Chemistry, 9(23), 8089-8095.