Cobalt-catalyzed cyclization of benzamides with alkynes: a facile route to isoquinolones with hydrogen evolution

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dc.contributor.authorMANOHARAN, RAMASAMYen_US
dc.contributor.authorJeganmohan, Masilamanien_US
dc.contributor.departmentDept. of Chemistryen_US
dc.date.accessioned2019-09-27T06:03:39Z
dc.date.available2019-09-27T06:03:39Z
dc.date.issued2018-09en_US
dc.description.abstractThe reaction of benzamides with alkynes assisted by an 8-aminoquinoline ligand in the presence of Co(OAc)2·4H2O and pivalic acid under an air atmosphere provided isoquinolone derivatives in good to excellent yields. In this reaction, the active Co(III) species is regenerated by the reaction of Co(I) species with pivalic acid under an air atmosphere with hydrogen evolution. The proposed mechanism was supported by competition experiments, deuterium labelling studies, radical scavenger experiments and kinetic studies.en_US
dc.identifier.citationOrganic & Biomolecular Chemistry, 16(37), 8384-8389.en_US
dc.identifier.issn1477-0520en_US
dc.identifier.issn1477-0539en_US
dc.identifier.sourcetitleOrganic & Biomolecular Chemistryen_US
dc.identifier.urihttp://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/4117
dc.identifier.urihttps://doi.org/10.1039/c8ob01924j
dc.language.isoenen_US
dc.publication.originofpublisherForeignen_US
dc.publisherRoyal Society of Chemistryen_US
dc.subjectN Bond Formationen_US
dc.subjectC-H Activationen_US
dc.subjectDirected Functionalizationen_US
dc.subjectInternal Oxidanten_US
dc.subjectAnnulationen_US
dc.subjectAccess; Amidesen_US
dc.subjectCarbonylationen_US
dc.subjectDerivativesen_US
dc.subjectOlefinationen_US
dc.subjectTOC-SEP-2019en_US
dc.subject2018en_US
dc.titleCobalt-catalyzed cyclization of benzamides with alkynes: a facile route to isoquinolones with hydrogen evolutionen_US
dc.typeArticleen_US

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