Stimuli-responsive synthetic ionophores for therapeutic applications

dc.contributor.authorCHATTOPADHAYAY, SANDIPen_US
dc.contributor.authorTALUKDAR, PINAKIen_US
dc.contributor.departmentDept. of Chemistryen_US
dc.date.accessioned2025-06-11T05:01:41Z
dc.date.available2025-06-11T05:01:41Z
dc.date.issued2025-04en_US
dc.description.abstractNature endowed different structurally and functionally complex transmembrane transporters to flux the ions to maintain the healthy functions of the cells by turning on or turning off the ion flow in the presence of external stimuli. Mimicking this stimuli-responsive behavior of natural transporters using synthetic analogs is currently an ongoing interest in the scientific community. This short review highlights the recent development of synthetic responsive ionophore systems. This includes pH, light, redox, enzyme, and multi-stimuli-controlled ionophores systems that have the potential to be utilized in different biomedical applications ranging from antibacterial activity to anticancer activity.en_US
dc.identifier.citationCurrent Opinion in Chemical Biology, 85, 102582.en_US
dc.identifier.issn1879-0402en_US
dc.identifier.issn1367-5931en_US
dc.identifier.sourcetitleCurrent Opinion in Chemical Biologyen_US
dc.identifier.urihttps://doi.org/10.1016/j.cbpa.2025.102582
dc.identifier.urihttp://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/10132
dc.language.isoenen_US
dc.publication.originofpublisherForeignen_US
dc.publisherElsevier B.V.en_US
dc.subjectAnimalsen_US
dc.subjectAnti-Bacterial Agentsen_US
dc.subjectAntineoplastic Agentsen_US
dc.subjectHumansen_US
dc.subjectHydrogen-Ion Concentrationen_US
dc.subjectIonophoresen_US
dc.subjectLighten_US
dc.subjectOxidation-Reductionen_US
dc.subject2025en_US
dc.titleStimuli-responsive synthetic ionophores for therapeutic applicationsen_US
dc.typeArticleen_US

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